【代表性论文】
1. Hui Zhao,
Hui Yang, Jinqiu Sun, Guoqiang Liang, Qianqian Zhao, Xiufang Zhang, Shengxian
Liang, Rui Guo, Li Zhong (2020）Mesenchymal
stem cells promote PD-L1expression in lung cancer cells. Cancer Research, 80(16):6011.
2. Cao, R, Islamoglu, H, Teskey, G, Gyurjian, K,
Abrahem, R, Onajole, O.K, Lun, S, Bishai, W, Kozikowski, A.P, Sathananthan, A,
Fraix, M, Zhong L, Stec, J,
Venketaraman, V. (2019). The preclinical candidate indole-2 carboxamide
improves immune responses to Mycobacterium tuberculosis infection in healthy
subjects and individuals with type 2 diabetes. International Microbiology. https://doi.org/10.1007/s10123-019-00086-0
3. Wang Q, Yang M, Zhang Y, Zhong L, Zheng X. (2019) Novel Combination Oncolytic Adenoviral
Gene Therapy Armed with Dm-dNK and CD40L for Breast Cancer. Current Gene Therapy. 19(1)：54-65.
4. Teskey G , Cao R, Islamoglu H, Medina A,
Prasad C, Prasad R, Sathananthan A, Fraix M, Subbian S, Zhong L, Venketaraman V. (2018) The Synergistic Effects of the Glutathione
Precursor, NAC and First-Line Antibiotics in the Granulomatous Response Against
Mycobacterium tuberculosis. Front Immunol.
9:2069.
5. Cao R, Teskey G, Islamoglu H, Abrahem R,
Munjal S, Gyurjian K, Zhong L, Venketaraman
V. (2018) Characterizing the Effects of Glutathione as an Immunoadjuvant in the
Treatment of Tuberculosis. Antimicrob
Agents Chemother. 24;62(11).
6. Wang J, Shi C, Wang J, Cao L, Zhong L, Wang D. (2017) MicroRNA-320a
is downregulated in non-small cell lung cancer and suppresses tumor cell growth
and invasion by directly targeting insulin-like growth factor 1 receptor. Oncol Lett. 13(5): 3247–3252.
7. Hao Li, Helen Ha, Xiaoxu Ding, Chay Bae,
Nicky Gazy, Li Zhong. (2018) DMH4, a
VEGFR2 Inhibitor, Effectively Suppresses Growth and Invasion of Lung Cancer
Cells. Journal of Applied Biomedicine,
16(1): 46-50.
8. Jeffrey Koury, Li Zhong, and Jijun Hao. (2017) Targeting Signaling Pathways in
Cancer Stem Cells for Cancer Treatment. Stem
Cells International, 2925869.
9. Jianfei Wang, Xu Dong, Li Cao, Mihai Covasa, Li Zhong. (2016) Association between telomere length and
diabetes mellitus: A meta-analysis. Journal
of International Medical Research, 44(6): 1156-1173.
10. Shen W, Cao Y, Cha L, Zhang X, Ying X, Zhang W, Ge K, Li W, Zhong L. (2015) Predicting linear
B-cell epitopes using amino acid anchoring pair composition. BioData Mining， 8:14.
11. Bae, C.;
Li, H.; Zhang, X.; Zhong, L. (2015) Investigating the effects of adipose
derived stem cells and fetal lung fibroblasts on lung cancer proliferation. Journal of Investigative Medicine.
63:210.
12. Gazy,
N.; Li, H.; Zhang, X.; Fuchs, S.; Venketaraman, V.; Martin, J.; Zhong, L. (2015) Investigating the efficacy of six chemical compounds on down-regulation
of TNFalpha production in macrophages in response to protein kinase C
activation by phorbol myristate acetate.
Journal of Investigative Medicine. 63:212.
13. Zhong L, Zhang X, Covasa M.
(2014) Emerging roles of lactic acid bacteria in protection against colorectal
cancer. World J Gastroenterol. 20(24):7878-86.
14. Lowe FJ,
Shen W, Zu J, Li J, Wang H, Zhang X, Zhong
L. (2014) A novel autoantibody test for the detection of pre-neoplastic
lung lesions. Mol Cancer 13:78.
15. Duca FA, Zhong L,
Covasa M. (2013). Reduced CCK signaling in obese-prone rats fed a high fat
diet. Horm Behav. 64(5):812-817.
16. Dong X, Yang M, Sun H, Lü J, Zheng Z, Li Z, Zhong L. (2013) Combined measurement of
CA 15-3 with novel autoantibodies improves diagnostic accuracy for breast
cancer. Onco Targets Ther. 6:273-9.
17. Zhang X, Shen W, Dong X, Fan J, Liu L, Gao X, Kernstine KH, Zhong L. (2013). Identification of
novel autoantibodies for detection of malignant mesothelioma. PLoS One, 8(8).
18. Zhang B, Zhang Z, Zhang X, Gao X, Kernstine KH, Zhong L. (2012) Serological antibodies
against LY6K as a diagnostic biomarker in esophageal squamous cell carcinoma.
Biomarkers. 17(4):372-8.
19. Zhou JH, Zhang B, Kernstine KH, Zhong L. Autoantibodies against MMP-7 as a novel diagnostic
biomarker in esophageal squamous cell carcinoma. (2011) World J Gastroenterol. 17(10):1373-8.
20. Zhong L, Zhang W, Zer C, Zhao L, Ge K, Gao X, Kernstine KH. (2010) Protein
Microarray: Sensitive and Effective Immunodetection for Drug Residues. BMC Biotechnology,10(1):12.
21. Dong X, Liu
A, Zer C, Feng J, Zhen Z, Yang M, Zhong
L. (2009) siRNA Inhibition of Telomerase Enhances the Anti-cancer Effect of
Doxorubicin in Breast Cancer Cells. BMC
Cancer, 9(1):133.
22. Guo R, Ma
H, Gao F, Zhong L, Ren J. (2009)
Metallothionein Alleviates Oxidative Stress-Induced Endoplasmic Reticulum
Stress and Myocardial Dysfunction. Journal
of Molecular and Cellular Cardiology, 47(2):228-37.
23. Guo R, Zhong L, Ren J. (2009) Overexpression
of aldehyde dehydrogenase-2 (ALDH2) attenuates chronic
alcohol exposure-induced apoptosis and alters Akt and Pim signaling in liver. Clinical and Experimental Pharmacology and
Physiology, 36:463-68.
24. Zhong L, Ge K, Zu JC, Zhao LH, Yen Y, Kernstine KH. (2008) Autoantibodies as
Potential Biomarkers for Breast Cancer. Breast
Cancer Research. 10(3):R40.
25. Zhong L, Coe S, Stromberg AJ, Khattar NH, Jett JR, Hirschowitz EA. (2006) Profiling
Tumor-associated Autoantibodies for Early Stage Non-Small Cell Lung Cancer. Journal
of Thoracic Oncology. 1(6):513-9.
26. Zhong L, Hidalgo GE, Stromberg AJ, Khattar NH, Jett JR, Hirschowitz EA. Protein Microarray as a Diagnostic Assay for
Non-Small Cell Lung Cancer. American
Journal of Respiratory and Critical Care Medicine. 2005,15;172(10):1308-14.
【研究团队】
2019年负责组建了“干细胞与生物医学研究”团队，目前已有郭蕊教授、梁胜贤副教授等研究人员加入了团队。
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