教育经历：  2015-2021，博士后          美国德克萨斯州西南医学中心

2010-2014，理学博士        南开大学

2007-2010，理学硕士        南开大学

2003-2007，理学学士        西南大学

工作经历：  2022-至今，校聘研究员      奥门金沙游戏

社会服务工作：曾担任Frontiers Cellular and Infection Microbiology, International Journal of Molecular Sciences, Applied Sciences, Molecules, Diseases, Journal of Cardiovascular Development and Disease 杂志审稿人。

执教课程：蛋白质与酶工程（本科生）。

【科研领域】

弓形虫与宿主互作关系；

弓形虫感染导致小鼠嗅觉缺陷的分子机制；

嗅觉相关的神经环路研究。     

【基金】

国家自然科学基金青年基金 (32202840)， 2023.01-2025.12   主持     30万

奥门金沙游戏高层次人才启动经费，          2022.09-2025.12   主持     50万

CPRIT Training Grant,                  2018.08-2021.01   主持     17万美元

1.      Hu X, O'Shaughnessy WJ, Reese ML. Loss of the conserved Alveolate kinase MAPK2 decouples Toxoplasma cell growth from the cell cycle. mBio, 2020 Nov 10; 11(6): e02517-20.

2.      Beraki T*, Hu X*, Broncel M, Young JC, O'Shaughnessy WJ, Borek D, Treeck M, Reese ML. Divergent kinase regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole. Proc Natl Acad Sci U S A. 2019 Mar 26; 116(13): 6365-6370. (*:共同一作)。

3.      Hu X, Binns D, Reese ML. The coccidian parasites Toxoplasma and Neospora dysregulate mammalian lipid droplet biogenesis, J Biol Chem. 2017 Jun 30;292(26):11009-11020. 

4.      Hu X*, Wu F*, Sun S, Yu W, Hu J. Human atlastin GTPases mediate differentiated fusion of endoplasmic reticulum membranes. Protein Cell. 2015 Apr;6(4):307-311. (*:共同一作)。

5.      Wu F*, Hu X*, Bian X, Liu X, Hu J. Comparison of human and Drosophila atlastin GTPases. Protein Cell. 2015 Feb;6(2):139-46. (*:共同一作)。

6.      Henriquez S, Hu X, O'Shaughnessy WJ, Reese ML. Identifying biochemical binding partners of a MAP kinase-like protein in Toxoplasma gondii. The FASEB Journal. 2020 April 17; 34(S1): 1-1.

7.      Back P, O'Shaughnessy WJ, Moon S, Dewangan PS, Hu X, Sha J, Wohlschlegel JA, Bradley PJ, Reese ML. Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required for Toxoplasma apical complex biogenesis. Proc Natl Acad Sci U S A. 2020, Jun 2;117(22):12164-12173.

8.      O'Shaughnessy WJ, Hu X, Beraki T, McDougal M, Reese ML. Loss of a conserved MAPK causes catastrophic failure in assembly of a specialized cilium-like structure in Toxoplasma gondii. Mol Biol Cell. 2020 Apr 15; 31(9): 881-888.

9.      Huang X, Zhou X, Hu X, Joshi AS, Guo X, Zhu Y, Chen Q, Prinz WA, Hu J. Sequences flanking the transmembrane segments facilitate mitochondrial localization and membrane fusion by mitofusin. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9863- E9872.

10.   Qi Y, Yan L, Yu C, Guo X, Zhou X, Hu X, Huang X, Rao Z, Lou Z, Hu J. Structures of human mitofusin 1 provide insight into mitochondrial tethering. J Cell Biol. 2016 Dec 5;215(5):621-629.)

11.   Yan L, Sun S, Wang W, Shi J, Hu X, Wang S, Su D, Rao Z, Hu J, Lou Z. Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion. J Cell Biol. 2015 Sep 14;210(6):961-72.

12.   Liu TY, Bian X, Sun S, Hu X, Klemm RW, Prinz WA, Rapoport TA, Hu J. Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastinmediated homotypic endoplasmic reticulum fusion. Proc Natl Acad Sci U S A. 2012 Aug 7;109(32): E2146-54.

13.   Ma B, Hu X, Zhao X, Zhang Y, Li C, Ma Z, Abbas SA, Chen W, Qu S, Li M. Pharmacokinetics, pharmacodynamics, and cytotoxicity of recombinant orallyadministrated long-lasting GLP-1 and its therapeutic effect on db/db mice. Exp Clin Endocrinol Diabetes. 2014 Apr; 122(4):215-21