1. Chen Y, Yang J, Wang Y, Shen W, Liu J, Yuan M, Hao X,
Zhong L, Guo R*. Identification and Analysis of Hub Genes in
Diabetic Cardiomyopathy: Potential Role of Cytochrome P450 1A1 in Mitochondrial
Metabolism and STZ-Induced Myocardial Dysfunction. Front. Cardiovasc. Med.
21 March 2022: Vol 9:835244.
2.
Zhao M, Lian A, Zhong L, Guo R*. The Regulatory Mechanism Between Lysosomes and Mitochondria in
the Aetiology of Cardiovascular Diseases. Acta
Physiologica. 2022 Feb; 234(2):e13757.
3.
李沛轩, 钟理, 郭蕊*. 重金属镉致心血管疾病的潜在机制及治疗对策. 中国科学: 生命科学, 2021, 51(9). Li P X, Zhong L, Guo R. Potential mechanism and
treatment of heavy metal cadmium-induced cardiovascular disease (in Chinese). Sci
Sin Vitae, 2021,51(9), doi: 10.1360/SSV-2021-0226.
4.
李钰, 赵倩倩, 梁胜贤, 钟理,郭蕊*. TFEB与线粒体稳态在脓毒症并发症中的调控机制. 中国科学: 生命科学, 2021, 51(9),. Li Y,
Zhao Q Q, Liang S X, et al. Regulation of TFEB and mitochondrial homeostasis
during sepsis complications (in Chinese). Sci Sin Vitae, 2021, 51(9), doi: 10.1360/SSV-2021-0213.
5.
Lochner A, Wang H, Reiter R, Guo R,
Zhou H. Editorial: Role of Mitochondrial Quality Control in Myocardial and
Microvascular Physiology and Pathophysiology. Front. Physiol., 08
September 2021. Volume 12, Article 745033.
6.
Liang G, Sun J, Liu Y, Liu D, Liang S, Guo R,
Zhong L. Identification of tumor associated genes using transcriptome analysis. Cancer Research, July 2021, 81 (13_Suppl): Abstract nr 2312.
7.
Liu J, Zhong L, Guo R*. The Role of
Posttranslational Modification and Mitochondrial Quality Control in
Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity. Feb
2021: 6635836.
8.
Yang H, Heyer J, Zhao H, Liang S, Guo R*,
Zhong L*. The Potential Role of Cathepsin K in Non-Small Cell Lung Cancer. Molecules.
Aug 2020,
25(18): 4136.
9. Zhao H, Yang H, Sun J, Liang G, Zhao Q, Zhang
X, Liang S, Guo R and
Zhong L. Mesenchymal stem cells promote PD-L1 expression in lung cancer cells. Cancer Research, Aug
2020, 80 (16) Supplement: a6011.
10. Guo R*, Yang H, Zhang Y, Li B, Liu X, Zhong L. The Potential Clinical Role of
Cathepsin K and Autophagy in the Prevention of Alcoholic Cardiomyopathy. Circulation 2019, 140 (Supplement 1): a15085.
11. Guo R, Wang Q, Nair R, Barnes S, Smith
D, Dai B, Robinson T, Nair S: Furosap, a novel Fenugreek seed extract improves
lean body mass and serum testosterone in a randomized, placebo-controlled,
double
blind clinical
investigation. Functional Foods in Health
and Disease. Nov 2018; 8(11): 508-519.
12. Guo R, Hua Y, Ren J, Bornfeldt K, Nair S:
Cardiomyocyte-Specific Disruption of Cathepsin K Protects Against
Doxorubicin-Induced Cardiotoxicity. Cell death & disease. Jun 2018, 9: 692.
13. Guo R, Nair S. Role of MicroRNA in Diabetic Cardiomyopathy: from Mechanism to
Intervention. Biochimica et Biophysica Acta (BBA) - Molecular Basis of
Disease. 2017, 1863(8):2070-2077.
14. Guo R, Hua Y, Rogers, O, Ren J, Nair S. Cathepsin K knockout protects against
cardiac dysfunction in diabetic mice. Scientific Reports. Aug. 2017,
7(1):8703.
15. Guo R, Rogers O, Nair S. Targeting Apelinergic System in
Cardiometabolic Disease. Current drug targets.
2017;18(15):1785-1791.
16. Guo R, Ren J, Nair S. Cathepsin K Knockout Inhibits Calcification, Migration and
Proliferation of Aortic Vascular Smooth Muscle Cells. Circulation 2017, 136 (Supplement 1).
17. Guo R, Nair S, Ren J. Role of the Cathepsin K/Calcineurin/NFATs Axis
in the Pathogenesis and Management of Diabetic Cardiomyopathy. Cardiology Plus. 2016, 1(3).
18. Guo R, Hua Y, Ren J, Bornfeldt
K, Nair S. Cardiomyocyte-Specific
Deletion of Cathepsin K Protects Against Doxorubicin-Induced Cardiac Dysfunction. Circulation 2016, 134 (Supplement 1).
19. Guo R, Hua Y, Rogers
O, Ren J, Nair S. Cathepsin
K knockout Preserves Cardiac Function in Diabetic Mice: Role of
Calcineurin/NFAT Signaling. Diabetes 2016, 65 (Supplement 1):
A101-A169.
20. Guo R, Zhang Y, Turdi S, Ren J:Adiponectin Knockout Accentuates High Fat
Diet-Induced Obesity and Cardiac Dysfunction: Role of Autophagy. Biochim
Biophys Acta. 2013, 1832(8):1136-1148.
21. Jiang S*, Guo R*, Zhang Y, Zuo Y, Ren
J: Heavy Metal Scavenger Metallothionein Mitigates Deep Hypothermia-Induced
Myocardial Contractile Anomalies: Role of Autophagy. Am J Physiol Endocrinol Metab. 2013,
304(1):e74-86.
22. Guo R, Hu N, Kandadi M, Ren J: Facilitated ethanol
metabolism promotes cardiomyocyte contractile dysfunction through autophagy in
murine Hearts. Autophagy. 2012, 8(4):593-608
23. Guo R, Ren J: Deficiency in AMPK attenuates ethanol-induced cardiac
contractile dysfunction through inhibition of autophagosome formation. Cardiovasc
Res. 2012, 94(3):480-491.
24. Guo R, Ren J. Aldehyde Dehydrogenase-2 (ALDH2) Ameliorates Chronic Alcohol
Ingestion-Induced Hepatic Steatosis and Inflammation. Experimental
Biology Annual Scientific Meeting, San Diego Convention Center, San Diego, CA,
Apr. 21-25, 2012; ORAL presentation. The FASEB Journal 2012, 26 (1), Supplement 405.8.
25. Ge W, Guo R, Ren J: AMP-dependent
kinase and autophagic flux are involved in aldehyde dehydrogenase-2-offered
protection against cardiac toxicity of ethanol. Free Radic Biol Med. 2011,
51(9):1736-1748.
26. Ma H, Guo R, Yu L, Zhang Y, Ren J:
Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion
injury: role of autophagy paradox and toxic aldehyde. Eur Heart J. 2011,
32(8):1025-1038.
27. Guo R, Ren J: Alcohol and acetaldehyde in public health: from marvel to
menace. Int J Environ Res Public Health. 2010, 7(4):1285-1301.
28. Guo R, Ma H,
Gao F, Zhong L, Ren J: Metallothionein alleviates oxidative stress-induced
endoplasmic reticulum stress and myocardial dysfunction. J Mol Cell Cardiol.
2009, 47(2):228-237.
【书籍章节发表】
1. Guo R, Nair S. Protease
Cathepsins in Cardiomyopathy: from Mechanism to Intervention. Proteases in human Diseases. p.447.
Chapter 21. Springer Nature. 2017.
DOI 10.1007/978-981-10-3162-5_21.
【教材出版】
1. 《细胞生物学实验教程(第二版)》(ISBN:978-7-03-071320-9),科学出版社,2022.10.
【研究团队】
干细胞与生物医学研究实验室,细胞代谢与心血管疾病研究团队:郭蕊教授课题组是奥门金沙游戏|中国有限公司唯一一支以细胞代谢和心血管并发症为主的研究团队,每年在细胞生物学专业(学硕)和生物与医药专业(专硕)招生,期待本科为基础医学、生理病理学、生物化学、细胞生物学、分子生物学、生物信息学、组学等相关专业优秀学子的加入。同时也欢迎代谢生物学与心血管疾病等相关领域的博士、博士后加入我们的团队。